tert-Butyl 4-(acetylsulfanyl)piperidine-1-carboxylate

tert-Butyl 4-(acetylsulfanyl)piperidine-1-carboxylate - Names and Identifiers

Name	1-Piperidinecarboxylic acid, 4-(acetylthio)-, 1,1-dimethylethyl ester
Synonyms	tert-Butyl 4-(acetylsulfanyl)piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-(acetylthio)-, 1,1-dimethylet... 1-Piperidinecarboxylic acid, 4-(acetylthio)-, 1,1-diMethylethyl este 1-Piperidinecarboxylic acid, 4-(acetylthio)-, 1,1-diMethylethyl ester 1-Piperidinecarboxylic acid, 4-(acetylthio)-, 1,1-dimethylethyl ester
CAS	141699-66-3

tert-Butyl 4-(acetylsulfanyl)piperidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C12H21NO3S
Molar Mass	259.36
Storage Condition	Room Temprature
MDL	MFCD13183580

tert-Butyl 4-(acetylsulfanyl)piperidine-1-carboxylate - Introduction

4-acetyl -1-piperidine carboxylic acid tert-butyl ester (also known as tert-butyl ester hydrochloride) is an organic compound, its molecular formula is C12H18N2O3.

Nature:
1. Appearance: 4-acetyl -1-piperidine carboxylic acid tert-butyl ester is a colorless transparent liquid.
2. Solubility: Soluble in organic solvents such as ethanol, ether and chloroform, insoluble in water.
3. melting point and boiling point: its melting point is -12 ℃, boiling point is 172-173 ℃.
4. chemical properties: it is a kind of ester compound, with the common properties of ester, such as ester exchange reaction with acid, alkali and so on.

Use:
4-acetyl -1-piperidinecarboxylic acid tert-butyl ester is mainly used as a pharmaceutical intermediate and a starting material for organic synthesis. It is commonly used in the preparation of compounds such as various drugs and pesticides.

Preparation Method:
A commonly used preparation method is synthesis by transesterification. The specific step is to react 4-acetyl-1-piperidinecarboxylic acid with tert-butanol under acidic conditions to produce an ester compound.

Safety Information:
When using and operating 4-acetyl -1-piperidine carboxylic acid tert-butyl ester, the following safety precautions should be paid attention:
1. 4-Acetyl-1-piperidinecarboxylic acid tert-butyl ester is irritating and direct contact with skin and eyes should be avoided.
2. use to maintain good ventilation conditions.
3. Avoid inhaling its vapor or mist, and should be equipped with appropriate personal protective equipment, such as safety glasses, gloves and masks.
4. Avoid contact with oxidants and strong acids during storage to avoid dangerous reactions.
5. if inhaled or ingested by mistake, seek medical attention immediately and bring packaging for processing.
Please pay attention to follow the correct use of chemicals and safe operation specifications to ensure safety during use.

Last Update：2024-04-09 19:05:46